Details about the disease

AON is an inherited neurological disorder characterised by a weakness in the hind limbs, eventually leading to weakness in the front limbs. Neurological signs of this condition seem to progress gradually over 3 to 4 years.

Clinical signs

Clinical signs usually begin between 7 and a half to 9 years of age. These signs include weakening and unsteady hind limbs and uncoordinated movement. The weakness eventually progresses to include the front limbs. When all limbs are affected, there may also be difficulty in swallowing.

How it is inherited

The disease is described as an autosomal recessive condition and is unique to Cocker Spaniels. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Can you test for PRA?

Yes, DNA test through Optigen 

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